What is Spravato?

• Spravato is an FDA-approved prescription medicine, used along with an antidepressant, for treatment-resistant depression (TRD) in adults.
• Spravato is the first and only NMDA receptor antagonist. It works differently than currently available oral antidepressants.
• Greater reduction of depression symptoms at four weeks compared to those who received a placebo plus an oral antidepressant.

How am I considered as a candidate?

• If you have struggled with treatment-resistant depression without adequate relief, schedule a consultation with our clinic to discuss whether Spravato may be an option for you.

Do I need to be referred by a psychiatrist?

• If referred by your psychiatrist, the consultation with be a 30-minute-long visit. Otherwise, the consultation will be an hour long visit to discuss your psychiatric condition and history.

• Nasal spray you self-administer at a certified Spravato treatment center, under the guidance and supervision of a healthcare professional.

How often will I need to come in for treatment?

• Spravato is taken twice a week for the first four weeks
• After the first four weeks, Spravato is taken once a week for a month
• After this, it is at your health care provider’s discretion

What are other things to keep in mind for the day of treatment?

• Patients should plan for a 2 hour visit and arrange for a ride home.
• You cannot take a benzodiazepine or stimulant medication on the day of treatment.

What are potential side effects from the medication?

• Most side effects are experienced within the treatment session and resolve before discharge. These most commonly include: sedation, disassociation, increased blood pressure. Your vital signs will be measured periodically to ensure your safety.

• Blood vessel disease (aneurysm)
• An abnormal connection between your blood vessels (arteriovenous malformation)
• History of bleeding in the brain
• Allergy to esketamine, ketamine or any of the ingredients in Spravato
• Uncontrolled high blood pressure
• Active substance abuse
• Plans to become pregnant, are pregnant, breastfeeding or planning to breastfeed.
• Please refer to spravato.com for more information. If eligible, please call us to schedule a consultation. We are available for any questions or concerns you may have.

Medical Director:

Marco A. Renazco, MD

Clinical Coordinator:

Keanan Beierle PA-C

Administrative Coordinator:

Melanie W. Renazco, J.D.

Phone number:

281-599-3313

Clinic Address:

24215 Kingsland Boulevard

Katy, TX 77494